Pitfalls in Predicting Hepatobiliary Drug Transport Using Human Sandwich-Cultured Hepatocytes
Vineet Kumar, Cindy Yanfei Li, Kazuya Ishida, Emese Kis, Zsuzsanna Gáborik, Jashvant D. Unadkat
Topics & Concepts
TransporterTaurocholic acidChemistryIn vivoDrugBiophysicsIn vitroCell biologyPharmacologyBiochemistryBiologyBile acidGeneBiotechnologyDrug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesDrug-Induced Hepatotoxicity and Protection