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Case Report: Detection of SARS-CoV-2 From Cerebrospinal Fluid in a 34-Month-Old Child With Encephalitis

Fatemeh Cheraghali, Alireza Tahamtan, Seyed Ahmad Hosseini, Mohammad Hadi Gharib, Abdolvahab Moradi, Hadi Razavi Nikoo, Alijan Tabarraei

2021Frontiers in Pediatrics17 citationsDOIOpen Access PDF

Abstract

Novel coronavirus (severe acute respiratory syndrome-coronavirus-2: SARS-CoV-2), which arose from Wuhan, China, has rapidly spread to other countries and developed into a pandemic. Although the respiratory manifestations of SARS-CoV-2 are well-documented, there is a considerable challenge regarding the direct and/or indirect infection in other organs. Several preliminary reports confirmed neurological manifestations in the SARS-CoV-2-infected patients. Here, we report the detection of SARS-CoV-2 from the nasopharyngeal swab and cerebrospinal fluid (CSF) in a 34-month-old child with encephalitis. This finding expands the spectrum of the neurological manifestations associated with SARS-CoV-2 infection.

Topics & Concepts

MedicineCerebrospinal fluidSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)EncephalitisPandemicCoronavirusCoronavirus disease 2019 (COVID-19)Respiratory systemBetacoronavirus2019-20 coronavirus outbreakPediatricsCoronaviridaeVirologyPathologyVirusInternal medicineOutbreakDiseaseInfectious disease (medical specialty)Long-Term Effects of COVID-19Infectious Encephalopathies and EncephalitisCOVID-19 Clinical Research Studies