Synthesis and structure–activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine
Ross D. Ballantine, Karol Al Ayed, Samantha J. Bann, Michael Hoekstra, Nathaniel I. Martin, Stephen A. Cochrane
Abstract
SAR studies on brevicidine and laterocidine yield new analogues with strong activity against multidrug-resistant Gram-negative bacteria.
Topics & Concepts
LipopeptideAntibioticsTerminal (telecommunication)StereochemistryMicrobiologyChemistryBiologyBacteriaComputer scienceGeneticsTelecommunicationsAntibiotic Resistance in BacteriaCancer therapeutics and mechanismsAntibiotic Use and Resistance