Glycyrrhizic acid mitigates hepatocyte steatosis and inflammation through ACE2 stabilization via dual modulation of AMPK activation and MDM2 inhibition
Longyue Zhou, Yun Yi, Bingqi Lin, Zhenwen Qiu, Chunxia Wang, Yuhao Li
Topics & Concepts
AMPKSteatosisHepatocyteInflammationChemistryAMP-activated protein kinaseDual roleDual (grammatical number)Cancer researchCell biologyInternal medicineMedicineProtein kinase ABiologyBiochemistryPhosphorylationIn vitroCombinatorial chemistryLiteratureArtPharmacological Effects of Natural CompoundsLiver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and Protection