Extracellular Vesicles Derived from Intermittent Hypoxia–Treated Red Blood Cells Impair Endothelial Function Through Regulating eNOS Phosphorylation and ET-1 Expression
Peng Lü, Yu Li, Xinwei Li, Yunhui Du, Linyi Li, Chaowei Hu, Jing Zhang, Yanwen Qin, Yongxiang Wei, Huina Zhang
Topics & Concepts
EnosEndothelial dysfunctionMedicineUmbilical veinProtein kinase BPI3K/AKT/mTOR pathwayEndotheliumPhosphorylationMAPK/ERK pathwayIntermittent hypoxiaEndocrinologyCell biologyHuman umbilical vein endothelial cellHypoxia (environmental)Internal medicineNitric oxideSignal transductionNitric oxide synthaseBiologyObstructive sleep apneaChemistryBiochemistryIn vitroOrganic chemistryOxygenExtracellular vesicles in diseasePregnancy and preeclampsia studiesObstructive Sleep Apnea Research