Litcius/Paper detail

Myocarditis in Cancer Patients: A Review of an Emerging Problem in Cardio-Oncology

Wolney de Andrade Martins, Eduardo Schlabendorff

2022ABC Heart Failure & Cardiomyopathy15 citationsDOIOpen Access PDF

Abstract

Patients with cancer have a multitude of etiological factors for developing myocarditis. Classical or conventional chemotherapy, radiation therapy, and, more recently, immunotherapy have all been described as possible etiologies of myocarditis. Furthermore, patients with cancer are immunosuppressed and more susceptible to bacterial and viral infections that can cause myocarditis. This narrative review addresses the many possible causes of myocarditis in patients with cancer. Particular emphasis will be given to immune checkpoint inhibitor (ICI)-induced myocarditis. ICI myocarditis generally affects male [...]

Topics & Concepts

MyocarditisMedicineCancerImmunotherapyEtiologyRadiation therapyChemotherapyImmunologyInternal medicineOncologyCancer Immunotherapy and BiomarkersCAR-T cell therapy researchPARP inhibition in cancer therapy