Gut metagenomic characteristics of ADHD reveal low <i>Bacteroides ovatus</i> -associated host cognitive impairment
Yan Li, Haiting Sun, Yufen Huang, Anqi Yin, Linjuan Zhang, Jiao Han, Yixuan Lyu, Xiangzhao Xu, Yifang Zhai, Huan Sun, Ping Wang, Jinyang Zhao, Silong Sun, Hailong Dong, Feng Zhu, Qiang Wang, Luís Augusto Rohde, Xuefeng Xie, Xin Sun, Lize Xiong
Abstract
induced enhanced neuronal activation in the hippocampal CA1 subregion. These findings indicate that gut microbial characteristics that are unique to patients with C-ADHD may be masked when considering a more heterogeneous group of patients. We link the gut microbiota to brain function in an ADHD animal model, suggesting the relevance of testing a potential bacteria-based intervention for some aspects of ADHD.
Topics & Concepts
BacteroidesAttention deficit hyperactivity disorderMetagenomicsGut floraBiologyMicrobiomePhenotypePsychologyPsychiatryImmunologyGeneticsBacteriaGeneTryptophan and brain disordersAttention Deficit Hyperactivity DisorderGut microbiota and health