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Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy

Sang Hyung Lee, Hyun Tae Lee, Heejin Lim, Yu-Jin Kim, Ui Beom Park, Yong‐Seok Heo

2020Biochemical and Biophysical Research Communications36 citationsDOI

Topics & Concepts

Monoclonal antibodyAntibodyImmunotherapyImmune checkpointCancer researchPD-L1Immunoglobulin light chainChemistryBlockadeImmune systemMedicineImmunologyBiochemistryReceptorCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionCAR-T cell therapy research
Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy | Litcius