Photodynamic bactericidal nanomaterials in food packaging: From principle to application
Chushu Zhang, Jiancheng Zhang, Shining Cao, Yueyi Tang, Mian Wang, Chunjuan Qu
Abstract
Compared to traditional preservatives, photodynamic inactivation (PDI) offers a promising bactericidal approach due to its nontoxic nature and low propensity for microbial resistance. In this paper, we initially investigate the principles and antibacterial mechanisms underlying PDI. We then review factors influencing PDI's germicidal efficacy in food preservation. Furthermore, we delve into the application potential of PDI nanomaterials, such as quantum dots, titanium dioxide, and graphene, in packaging and films. Special attention is given to the impact of PDI treatment on food quality and the potential for microbial tolerance development. Last, we discuss the migration and safety of PDI nanomaterials. The chemical basis of PDI involves the generation of reactive oxygen species through the activation of endogenous or exogenous photosensitizers. Its primary antibacterial mechanisms encompass the disruption of cell membranes, impairment of cellular functions, and inhibition of quorum sensing. The multi-target action of PDI significantly reduces the likelihood of resistance development. PDI has great potential for application in the field of antibacterial packaging. The information contained in this paper will provide effective reference for the design of new antibacterial packaging.