GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma
Ruixin Sun, Yifan Liu, Yansha Sun, Min Zhou, Yi Wang, Bizhi Shi, Hua Jiang, Zonghai Li
Topics & Concepts
Hepatocellular carcinomaCancer researchHepatic carcinomaGLUT1ChemistryBiologyPharmacologyMedicineInternal medicineGlucose transporterInsulinCAR-T cell therapy researchImmune Cell Function and InteractionPhagocytosis and Immune Regulation