Low-Frequency Sonophoresis as an Active Approach to Potentiate the Transdermal Delivery of Agomelatine-Loaded Novasomes: Design, Optimization, and Pharmacokinetic Profiling in Rabbits
Mai Ahmed Tawfik, Magdy I. Mohamed, Mina Ibrahim Tadros, Sara Nageeb El-Helaly
Topics & Concepts
TransdermalBioavailabilityPharmacokineticsFirst pass effectPermeationOleic acidEx vivoBiomedical engineeringChemistryCmaxDrug deliveryPharmacologyIn vivoChromatographyPenetration (warfare)Materials scienceMedicineNanotechnologyBiochemistryMathematicsIn vitroBiologyOperations researchMembraneBiotechnologyAdvancements in Transdermal Drug DeliveryMicroencapsulation and Drying ProcessesBee Products Chemical Analysis