Targeted delivery of celastrol to renal interstitial myofibroblasts using fibronectin-binding liposomes attenuates renal fibrosis and reduces systemic toxicity
Rui Li, Yanping Li, Jinhang Zhang, Qinhui Liu, Tong Wu, Jian Zhou, Hui Huang, Qin Tang, Cuiyuan Huang, Ya Huang, Zijing Zhang, Guorong Zhang, Yingnan Zhao, Liang Ma, Yanhuan Feng, Li Mo, Min Han, Jinhan He
Topics & Concepts
FibrosisKidneyMedicineToxicityPharmacologyMyofibroblastFibronectinLiposomeKidney diseasePathologyCancer researchChemistryInternal medicineExtracellular matrixBiochemistryNanoparticle-Based Drug DeliveryCell Adhesion Molecules ResearchExtracellular vesicles in disease