Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a
Miguel Salinas, Pascal Kessler, Dominique Douguet, Daad Sarraf, Nicolò Tonali, Robert Thaï, Denis Servent, Éric Lingueglia
Topics & Concepts
Acid-sensing ion channelIon channelBiophysicsChemistrySodium channelHelix (gastropod)Cell biologyBiologyBiochemistryReceptorSnailEcologySodiumOrganic chemistryIon Transport and Channel RegulationIon channel regulation and functionIon Channels and Receptors