A costimulatory chimeric antigen receptor targeting TROP2 enhances the cytotoxicity of NK cells expressing a T cell receptor reactive to human papillomavirus type 16 E7
Mansour Poorebrahim, Isaac Quiros‐Fernandez, Frederik Marmé, Stefan Burdach, Ángel Cid-Arregui
Topics & Concepts
T-cell receptorCytotoxic T cellAntigenChimeric antigen receptorBiologyAdoptive cell transferCD8Cancer researchT cellCD28Cancer immunotherapyImmunotherapyCD3ImmunologyImmune systemIn vitroBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionNeuroblastoma Research and Treatments