Design, synthesis, and anticancer evaluation of novel andrographolide derivatives bearing an α,β-unsaturated ketone moiety
Wei Cai, Jieyi Li, Cheng Chen, Jia‐Jia Wu, Jiabin Li, Xiaowen Xue
Topics & Concepts
AndrographolideChemistryApoptosisCell cycleCell cycle checkpointCell growthKetoneMoietyCell cultureInhibitory postsynaptic potentialFlow cytometryCellStereochemistryIC50BiochemistryIn vitroMolecular biologyBiologyOrganic chemistryGeneticsNeuroscienceAndrographolide Research and ApplicationsPARP inhibition in cancer therapyBerberine and alkaloids research