Gradient tumor microenvironment-promoted penetrating micelles for hypoxia relief and immunosuppression reversion in pancreatic cancer treatment
Yifan Luo, Chao Li, Yiwen Zhang, Peixin Liu, Hongyi Chen, Zhenhao Zhao, Yu Wang, Zheng Zhou, Haolin Song, Boyu Su, Chufeng Li, Xuwen Li, Tongyu Zhang, Haoyu You, Yuxing Wu, Zonghua Tian, Shilin Zhang, Yun Guo, Hongrui Fan, Qinjun Chen, Chen Jiang, Tao Sun
Topics & Concepts
Tumor microenvironmentDrug deliveryCancer researchTumor hypoxiaPancreatic cancerStromaHypoxia (environmental)MicelleGemcitabinePancreatic tumorChemistryMedicineMaterials scienceChemotherapyCancerImmunologyNanotechnologyInternal medicineRadiation therapyTumor cellsOxygenImmunohistochemistryOrganic chemistryPhysical chemistryAqueous solutionPancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and MetabolismNanoplatforms for cancer theranostics