Litcius/Paper detail

Nucleotide addition and cleavage by RNA polymerase II: Coordination of two catalytic reactions using a single active site

Ilona Christy Unarta, Eshani C. Goonetilleke, Dong Wang, Xuhui Huang

2022Journal of Biological Chemistry18 citationsDOIOpen Access PDF

Abstract

in the nucleotide addition and intrinsic cleavage reactions.

Topics & Concepts

NucleotideProcessivityPolymeraseChemistryRNA polymerase IIActive siteRNAStereochemistryBiochemistryDNABiologyCatalysisGeneGene expressionPromoterRNA and protein synthesis mechanismsDNA and Nucleic Acid ChemistryRNA modifications and cancer