Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections
Blake W. Buchan, Sam Windham, Joan‐Miquel Balada‐Llasat, Amy L. Leber, Amanda Harrington, Ryan F. Relich, Caitlin N. Murphy, Jennifer Dien Bard, Samia N. Naccache, Shira Ronen, Amanda Hopp, Derya Mahmutoglu, Matthew L. Faron, Nathan A. Ledeboer, Amanda Carroll, Hannah K. Stone, Oluseun Akerele, Kathy Everhart, Andrew Bonwit, Christina Kwong, Rebecca J. Buckner, Del A. Warren, Randal C. Fowler, Sukantha Chandrasekaran, Holly Huse, Shelley Campeau, Romney M. Humphries, Corrin Graue, Angela Huang
Abstract
genomic copies/ml by the PN panel. Viral targets were identified by the PN panel in 17.7% of specimens tested, of which 39.1% were detected in conjunction with a bacterial target. A review of patient medical records, including clinically prescribed antibiotics, revealed the potential for antibiotic adjustment in 70.7% of patients based on the PN panel result, including discontinuation or de-escalation in 48.2% of patients, resulting in an average savings of 6.2 antibiotic days/patient.