Inhibition of FGFR2 enhances chemosensitivity to gemcitabine in cholangiocarcinoma through the AKT/mTOR and EMT signaling pathways
Rattanaporn Jaidee, Veerapol Kukongviriyapan, Laddawan Senggunprai, Auemduan Prawan, Apinya Jusakul, Phatthamon Laphanuwat, Sarinya Kongpetch
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayCell growthCancer researchCell cycleAngiogenesisDownregulation and upregulationClonogenic assayChemistryBiologyCellSignal transductionCell biologyBiochemistryGeneFibroblast Growth Factor ResearchCholangiocarcinoma and Gallbladder Cancer StudiesPancreatic and Hepatic Oncology Research