Reagent-free intramolecular hydrofunctionalization: a regioselective 6-<i>endo-dig</i> cyclization of <i>o</i>-alkynoylphenols
Chanhyun Jung, Siyuan Li, Kwanghee Lee, Mayavan Viji, Heesoon Lee, Soonsil Hyun, Kiho Lee, Young Kee Kang, Chhabi Lal Chaudhary, Jae‐Kyung Jung
Abstract
Solvent-directed intramolecular hydrofunctionalization of readily available o -alkynoylphenols 1 was successfully achieved under reagent-free conditions.
Topics & Concepts
ReagentRegioselectivityIntramolecular forceDigChemistrySolventCombinatorial chemistryMedicinal chemistryOrganic chemistryCatalysisComputer scienceComputer securityCatalytic C–H Functionalization MethodsCatalytic Alkyne ReactionsCatalytic Cross-Coupling Reactions