Biological applications of synthetic anion transporters
Nasim Akhtar, Oindrila Biswas, Debasis Manna
Abstract
ion transport mediated antibacterial activities have also been successfully used against clinically relevant bacterial strains, many of which are tolerant towards commercial antibiotics. Recent developments in the chloride ion transport mediated biological activities of anionophores have been mainly discussed in this article. It also highlights other aspects, such as design criteria, targeted delivery options, and others, which can be useful for the further development of selective anionophores for specific biological applications.
Topics & Concepts
Transmembrane proteinTransporterChemistryBacteriaSmall moleculeAntibioticsCombinatorial chemistryIon transporterBiochemistryBiophysicsMicrobiologyBiologyMembraneGeneGeneticsReceptorAmino Acid Enzymes and MetabolismDNA and Nucleic Acid ChemistryMolecular Sensors and Ion Detection