microRNA-15b-5p shuttled by mesenchymal stem cell-derived extracellular vesicles protects podocytes from diabetic nephropathy via downregulation of VEGF/PDK4 axis
Tiantian Zhao, Qingsong Jin, Lili Kong, Dongdong Zhang, Yaqin Teng, Liangyan Lin, Xiaoyan Yao, Yongjun Jin, Minglong Li
Topics & Concepts
Mesenchymal stem cellPDK4Diabetic nephropathyCell biologymicroRNADownregulation and upregulationFlow cytometryAngiogenesisVascular endothelial growth factor AChemistryExtracellular vesicleCancer researchBiologyMicrovesiclesMolecular biologyBiochemistryVascular endothelial growth factorEndocrinologyDiabetes mellitusGeneVEGF receptorsExtracellular vesicles in diseasePregnancy and preeclampsia studiesCardiovascular Disease and Adiposity