Insight into the mechanism of tetrachlorobisphenol A (TCBPA)-induced proliferation of breast cancer cells by GPER-mediated signaling pathways
Bingli Lei, Qianqian Tang, Su Sun, Xiaolan Zhang, Yaoyao Huang, Lanbing Xu
Topics & Concepts
GPERSKBR3Estrogen receptorProtein kinase BSignal transductionCell growthPI3K/AKT/mTOR pathwayDownregulation and upregulationCell biologyPhosphorylationEstrogen receptor alphaChemistryBiologyCancer cellCancer researchEndocrinologyCancerBiochemistryBreast cancerHuman breastGeneticsGeneEstrogen and related hormone effectsEffects and risks of endocrine disrupting chemicalsInflammatory mediators and NSAID effects