Cell cycle exits and U-turns: Quiescence as multiple reversible forms of arrest
Martha S. Johnson, Jeanette Gowen Cook
Abstract
phase. This brief review describes recent advances in our understanding of how and when quiescence is initiated and maintained in mammalian cells. We highlight the growing appreciation for quiescence as a collection of context-dependent distinct states.
Topics & Concepts
Cell biologyContext (archaeology)Cell cycleCarcinogenesisBiologyCell growthCell cycle checkpointCellCell cycle progressionGeneticsCancerPaleontologyCancer-related Molecular PathwaysUbiquitin and proteasome pathwaysMicrotubule and mitosis dynamics