The Cell Biology of LRRK2 in Parkinson's Disease
Ahsan Usmani, Farbod Shavarebi, Annie Hiniker
Abstract
genes, may highlight cellular pathways more broadly disrupted in PD.
Topics & Concepts
LRRK2BiologyRabCell biologyDiseaseComputational biologyGeneticsKinaseMutationCytoskeletonPoint mutationCellSubcellular localizationSignal transductionBioinformaticsCell typeMechanism (biology)Human diseaseProtein kinase ACancer researchModel organismCytoplasmAcetylationProtein–protein interactionActin cytoskeletonParkinson's Disease Mechanisms and TreatmentsParkinson's Disease and Spinal DisordersNeurological disorders and treatments