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Absorption, metabolism and excretion of [14C]-sotorasib in healthy male subjects: characterization of metabolites and a minor albumin-sotorasib conjugate

Irene Vuu, Upendra P. Dahal, Zhe Wang, Xiaomeng Shen, John B. Rodgers, Jan L. Wahlstrom, Brett E. Houk

2022Cancer Chemotherapy and Pharmacology23 citationsDOI

Topics & Concepts

UrineChemistryExcretionMetabolismFecesAlbuminPharmacokineticsInternal medicineEndocrinologyBlood plasmaMetaboliteGlutathioneBiochemistryEnzymeBiologyMedicinePaleontologyFibroblast Growth Factor ResearchLung Cancer Research StudiesChronic Myeloid Leukemia Treatments
Absorption, metabolism and excretion of [14C]-sotorasib in healthy male subjects: characterization of metabolites and a minor albumin-sotorasib conjugate | Litcius