Intracerebroventricular enzyme replacement therapy in patients with neuronopathic mucopolysaccharidosis type II: Final report of 5-year results from a Japanese open-label phase 1/2 study
Joo-Hyun Seo, Motomichi Kosuga, Takashi Hamazaki, Haruo Shintaku, Torayuki Okuyama
Topics & Concepts
Enzyme replacement therapyMedicineAdverse effectHunter syndromeMucopolysaccharidosis type IIInternal medicineInterim analysisCerebrospinal fluidMucopolysaccharidosis type IGastroenterologyClinical trialDiseaseLysosomal Storage Disorders ResearchGlycogen Storage Diseases and MyoclonusIntestinal Malrotation and Obstruction Disorders