Litcius/Paper detail

Disclosing Cyclic(Alkyl)(Amino)Carbenes as One‐Electron Reductants: Synthesis of Acyclic(Amino)(Aryl)Carbene‐Based Kekulé Diradicaloids

Avijit Maiti, Benedict J. Elvers, Sachinath Bera, Felix Lindl, Ivo Krummenacher, Prasanta Ghosh, Holger Braunschweig, Cem B. Yildiz, Carola Schulzke, Anukul Jana

2022Chemistry - A European Journal19 citationsDOIOpen Access PDF

Abstract

Herein, we disclose cyclic(alkyl)(amino)carbenes (CAACs) to be one-electron reductants under the formation of a transient radical cation as indicated by EPR spectroscopy. The disclosed CAAC reducing reactivity was used to synthesize acyclic(amino)(aryl)carbene-based Thiele and Chichibabin hydrocarbons, a new class of Kekulé diradicaloids. The results demonstrate CAACs to be potent organic reductants. Notably, the acyclic(amino)(aryl)carbene-based Chichibabin's hydrocarbon shows an appreciable population of the triplet state at room temperature, as evidenced by both variable-temperature NMR and EPR spectroscopy.

Topics & Concepts

CarbeneChemistryArylElectron paramagnetic resonanceAlkylReactivity (psychology)Medicinal chemistryPhotochemistryOrganic chemistryCatalysisPhysicsAlternative medicineNuclear magnetic resonanceMedicinePathologyN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCyclopropane Reaction MechanismsOrganoboron and organosilicon chemistry