Pushing beyond specifications: Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommendations
Dominik Nörz, André Frontzek, Ulrich Eigner, Lisa Oestereich, Dominic Wichmann, Stefan Kluge, Nicole Fischer, Martin Aepfelbacher, Susanne Pfefferle, Marc Lütgehetmann
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)MedicineViral loadRespiratory systemMatrix (chemical analysis)ChromatographyVirologyChemistryVirusPathologyInternal medicineDiseaseInfectious disease (medical specialty)SARS-CoV-2 detection and testingMolecular Biology Techniques and ApplicationsBiosensors and Analytical Detection