E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
Hui Li, Ning Wang, Yu Jiang, Haofei Wang, Zengfeng Xin, Huazhang An, Hao Pan, Wangqian Ma, Ting Zhang, Xiaojian Wang, Wenlong Lin
Topics & Concepts
Ubiquitin ligaseUbiquitinInflammationCell biologyProinflammatory cytokineSignal transductionTumor necrosis factor alphaChemokinePhosphorylationKinaseBiologyDownregulation and upregulationChemistryImmunologyBiochemistryGeneNF-κB Signaling PathwaysImmunotherapy and Immune ResponsesUbiquitin and proteasome pathways