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Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells

Skylar S. Wright, P. Hima Kumari, Víctor Fraile-Ágreda, Chengliang Wang, Sonia Shivcharan, Shirin Kappelhoff, Eleonora Margheritis, Alyssa Matz, Swathy O. Vasudevan, Ignacio Rubio, Michael Bauer, Beiyan Zhou, Sivapriya Kailasan Vanaja, Katia Cosentino, Jianbin Ruan, Vijay Rathinam

2024Cell93 citationsDOIOpen Access PDF

Topics & Concepts

Bystander effectPyroptosisBiologyExtracellular vesiclesCell biologyTransplantationExtracellularVesicleMicrovesiclesImmunologyMembraneInflammationGeneticsInflammasomeMedicineGeneSurgerymicroRNAInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideStreptococcal Infections and Treatments
Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells | Litcius