Flavonoid-statin interactions causing myopathy and the possible significance of OATP transport, CYP450 metabolism and mevalonate synthesis
Joshua Zechner, Susan M. Britza, Rachael Farrington, Roger W. Byard, Ian Musgrave
Topics & Concepts
StatinPharmacologySLCO1B1HMG-CoA reductaseMyopathyReductaseDrug interactionDrugPrenylationChemistryMedicineBiochemistryInternal medicineEnzymePharmacogeneticsGeneGenotypePlant biochemistry and biosynthesisComputational Drug Discovery MethodsPharmacogenetics and Drug Metabolism