Electrochemical aptasensor for analyzing alpha-fetoprotein using RGO–CS–Fc nanocomposites integrated with gold–platinum nanoparticles
Wenzhan Li, Min Chen, Jintao Liang, Chunting Lu, Min Zhang, Fangrong Hu, Zhide Zhou, Guiyin Li
Abstract
. In addition, the approach was manifested to have good selectivity, reproducibility, and stability. The fabricated aptasensor had a good recovery rate of 102.36% to 118.09% in real human serum samples. This work demonstrates that the electrochemical aptasensor is a useful tool for analyzing AFP inexpensively, rapidly, and accurately.
Topics & Concepts
AptamerNanocompositeElectrochemistryPlatinumSelectivityPlatinum nanoparticlesColloidal goldNanotechnologyMaterials scienceNanoparticleAlpha-fetoproteinReproducibilityChemistryChromatographyElectrodeCatalysisOrganic chemistryMolecular biologyPhysical chemistryHepatocellular carcinomaBiologyCancer researchAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryBiosensors and Analytical Detection