A reduction of primary cilia but not hedgehog signaling disrupts morphogenesis in testicular organoids
Taylor Goldsmith, Sadman Sakib, Dennis A. Webster, Daniel F. Carlson, Frans van der Hoorn, Ina Dobrinski
Topics & Concepts
CiliumCell biologyMorphogenesisBiologyHedgehogHedgehog signaling pathwaySmoothenedGene knockdownCyclopamineIntraflagellar transportSignal transductionCell cultureGeneticsGeneFlagellumGenetic and Kidney Cyst DiseasesHedgehog Signaling Pathway StudiesRenal and related cancers