Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity
Joanne D. Tejero, Rebecca S. Hesterberg, Stanislav Drápela, Didem Ilter, Devesh Raizada, Felicia Lazure, Hossein Kashfi, Min Liu, Leonardo Silvane, Dorina Avram, Juan Fernández-García, John M. Asara, Sarah‐Maria Fendt, John L. Cleveland, Ana P. Gomes
Topics & Concepts
BiologyImmunityCD8ImmunologyMethylmalonic acidCytotoxic T cellImmune systemCancer researchEndocrinologyGeneticsIn vitroHomocysteineImmune Cell Function and InteractionImmune cells in cancerCancer Immunotherapy and Biomarkers