Generation and reaction of alkyl radicals in open reaction vessels
Elene Tatunashvili, Christopher S. P. McErlean
Abstract
An operationally simple process to transform alkyl iodides into reactive alkyl radicals is described. Aryl diazonium salts react with Hantzsch esters and molecular oxygen to give aryl radicals, which participate in halogen atom transfers to give alkyl radicals. These intermediates react with a variety of acceptors. The reaction cascade occurs at room temperature, in open reaction vessels, with short reaction times.
Topics & Concepts
ChemistryRadicalAlkylHalogenArylPhotochemistryRadical disproportionationReactive intermediateOrganic chemistryCatalysisDisproportionationRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsFluorine in Organic Chemistry