526O High activity of nivolumab in patients with pathogenic exonucleasic domain POLE (edPOLE) mutated Mismatch Repair proficient (MMRp) advanced tumours
Benoı̂t Rousseau, Ivan Bièche, Éric Pasmant, Victor Simmet, Nadim Hamzaoui, Julien Masliah‐Planchon, Damien Pouessel, Amandine Bruyas, Paule Augereau, Jean‐Jacques Grob, Frédéric Rolland, Esma Saâda-Bouzid, Romain Cohen, Olivier Bouché, Natalie Hoog-Labouret, Frédéric Legrand, Clotilde Simon, Assia Lamrani-Ghaouti, Sylvie Chevret, Aurélien Marabelle
Topics & Concepts
MedicineNivolumabInternal medicineLynch syndromeCancerOncologyCohortColorectal cancerImmunotherapyDNA mismatch repairCancer Genomics and DiagnosticsCancer Immunotherapy and BiomarkersGenetic factors in colorectal cancer