Interaction of Staphylococcus aureus and Acinetobacter baumannii during <i>In Vitro</i> β-Lactam Exposure
Nicholas M. Smith, Alexa Ang, Fanny Tan, Katelyn Macias, Sarah L. James, Jasleen Sidhu, Justin R. Lenhard
Abstract
We sought to determine if Acinetobacter baumannii is capable of altering the pharmacodynamics of an antistaphylococcal β-lactam. Two strains of methicillin-susceptible Staphylococcus aureus (MSSA) and two A. baumannii isolates were studied in 24-h static time-killing experiments under monoculture or coculture conditions.
Topics & Concepts
Acinetobacter baumanniiStaphylococcus aureusMicrobiologyAcinetobacterBiologyMicrococcaceaeIn vitroLactamAntibioticsAntibacterial agentBacteriaChemistryPseudomonas aeruginosaGeneticsStereochemistryAntibiotic Resistance in BacteriaAntibiotics Pharmacokinetics and EfficacyAntimicrobial Resistance in Staphylococcus