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Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

Shuai Yuan, Lei Peng, Jonathan J. Park, Yingxia Hu, Swapnil C. Devarkar, Matthew B. Dong, Qi Shen, Shenping Wu, Sidi Chen, Ivan B. Lomakin, Yong Xiong

2020Molecular Cell204 citationsDOIOpen Access PDF

Topics & Concepts

BiologyInternal ribosome entry siteRibosomeCell biologyMessenger RNARNAVirologyTranslation (biology)Viral entryProtein biosynthesisRNA virusVirusGeneticsViral replicationGeneSARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyViral Infections and Immunology Research
Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA | Litcius