Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1
Raúl Vivar, Claudio Humeres, Renatto Anfossi, Samir Bolívar, Mabel Catalán, Joseph A. Hill, Sergio Lavandero, Guillermo Dı́az-Araya
Topics & Concepts
RegulatorGene silencingTransforming growth factorFOXO1MyofibroblastCell biologyCancer researchDownregulation and upregulationChemistryProtein kinase BInternal medicineBiologySignal transductionEndocrinologyFibrosisMedicineBiochemistryGeneFOXO transcription factor regulationSignaling Pathways in DiseaseCardiac Fibrosis and Remodeling