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Palladium acetate assisted synthesis of five-membered <i>N-</i> polyheterocycles

Navjeet Kaur, Yamini Verma, Pooja Grewal, Neha Ahlawat, Pranshu Bhardwaj, Nirmala Kumari Jangid

2020Synthetic Communications34 citationsDOI

Abstract

The metal-assisted synthesis of heterocyclic compounds is known to be one of the extremely developing as well as significant concepts of organic chemistry. Because of their expensive, complex working of the instrument and difficult procedures, the methodologies used earlier for the heterocycle synthesis were less amicable to the researchers. The Pd(OAc)2-mediated cyclic reactions have been recognized to be very effective for both the stereoselective as well as regioselective formation of the 5-membered N-bearing heterocyclic compounds. The different uses of palladium acetate, as a catalyst in the formation of 5-membered N-containing polyheterocycles, are covered in this review article.

Topics & Concepts

ChemistryPalladiumRegioselectivityStereoselectivityCatalysisCombinatorial chemistryOrganic synthesisOrganic chemistryMetalReaction conditionsCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsCatalytic Cross-Coupling Reactions
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