Daily generation of a footward fluid shift attenuates ocular changes associated with head-down tilt bed rest
Justin S. Lawley, Gautam Babu, Sylvan L. J. E. Janssen, Lonnie G. Petersen, Christopher M. Hearon, Katrin A. Dias, Satyam Sarma, Michael A. Williams, Louis A. Whitworth, Benjamin D. Levine
Abstract
Choroid measurements appear to be sensitive to changes in gravitational gradients, as well as periods of head-down tilt (HDT) bed rest, suggesting that they are potential indicators of early ocular remodeling and could serve to evaluate the efficacy of countermeasures for SANS. Eight hours of lower body negative pressure (LBNP) daily attenuates the choroid expansion associated with 3 days of strict -6° HDT bed rest, indicating that LBNP may be an effective countermeasure for SANS.
Topics & Concepts
Bed restHead-Down TiltMedicineTilt (camera)Rest (music)Lower bodyBody fluidChoroidWeightlessnessHead tiltAnesthesiaInternal medicineCardiologyOphthalmologyBiologyNeuroscienceRetinaPhysicsEngineeringMechanical engineeringAstronomySpaceflight effects on biologyCorneal surgery and disordersOptical Imaging and Spectroscopy Techniques