Visible-Light-Induced <i>N</i>-Acylation of Sulfoximines
Pan Qiu, Xuelun Duan, Ming Li, Yubin Zheng, Wangze Song
Abstract
A metal-, base-, and additive-free N-acylation of sulfoximines was developed under mild conditions using organic photoredox catalyst. This green strategy featured broad substrate scope, good compatibility with air, and high yields (up to 96%). It could be further applied to amino acid modifications and α-keto N-acyl sulfoximine synthesis without any complicated transformations or operations.
Topics & Concepts
AcylationChemistryCombinatorial chemistryPhotoredox catalysisCompatibility (geochemistry)Substrate (aquarium)CatalysisScope (computer science)Organic baseOrganic chemistryPhotocatalysisChemical engineeringProgramming languageEngineeringGeologyComputer scienceOceanographySynthesis and Catalytic ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques