Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo
Ning Liu, Mingxing Ma, Na Qu, Ruizhe Wang, Hao Chen, Fangzhu Hu, Song Gao, Fengping Shan
Topics & Concepts
In vivoCancer researchHeLaIn vitroEpithelial–mesenchymal transitionGene knockdownNaltrexoneApoptosisCervical cancerMetastasisMesenchymal stem cellCancer cellMacrophage polarizationMedicineCancerPharmacologyChemistryMacrophageBiologyReceptorPathologyOpioidInternal medicineBiochemistryBiotechnologyCancer, Stress, Anesthesia, and Immune ResponseImmune cells in cancerNeuropeptides and Animal Physiology