Verteporfin-loaded supramolecular micelles for enhanced cisplatin-based chemotherapy <i>via</i> autophagy inhibition
Junwei Ye, Bo Yu, Haitao Hu, Dongfang Zhou, Qiao Jin, Jian Ji, Zhe Tang
Abstract
Cisplatin and autophagy inhibitor verteporfin co-loaded zwitterionic supramolecular micelles were fabricated. The therapeutic efficacy of cisplatin-based chemotherapy could be enhanced by the inhibition of autophagy.
Topics & Concepts
MicelleCisplatinAutophagyChemistrySupramolecular chemistryBiophysicsMaterials scienceCombinatorial chemistryBiochemistryApoptosisOrganic chemistryChemotherapyBiologyAqueous solutionGeneticsCrystal structureNanoparticle-Based Drug DeliveryAdenosine and Purinergic SignalingNanomaterials for catalytic reactions