Glucose transporter 1 (GLUT1)-targeting and hypoxia-activated mitochondria-specific chemo-thermal therapy via a glycosylated poly(amido amine)/celastrol (PAMAM/Cel) complex
Guijie Wei, Jianhua Chen, Ziqi Jing, Yanyi Li, Zhihui Li, Wei Zheng, Xiu-Rui Sun, Wenwen Zhao, Zhe Zhang, Xue Wang, Hong-Cui Han, Chu Li, Yujie Zhang, Pengkai Ma
Topics & Concepts
GLUT1ChemistryMitochondrionTumor microenvironmentGlucose transporterCancer cellTumor hypoxiaCancer researchBiochemistryCytotoxicityBiophysicsPharmacologyCell biologyCancerBiologyMedicineRadiation therapyGeneticsInternal medicineIn vitroEndocrinologyTumor cellsInsulinNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismNanoparticle-Based Drug Delivery