Dual-function microneedle array for efficient photodynamic therapy with transdermal co-delivered light and photosensitizers
Huiting Zhao, Xu Wang, Zhanhui Geng, Naixin Liang, Qin Li, Xiaoming Hu, Zewen Wei
Abstract
while realizing better treatment effects. As a result, the skin damage and the burden on the metabolic system have been alleviated. The DfMNA has a remarkably reduced photosensitizer amount and, for the first time, realized transdermal delivery of therapeutic light for PDT, thus avoiding the disadvantages of existing PDT methodologies.
Topics & Concepts
PhotosensitizerPhotodynamic therapyTransdermalBiomedical engineeringBlue lightMaterials scienceMedicinePharmacologyChemistryOptoelectronicsPhotochemistryOrganic chemistryPhotodynamic Therapy Research StudiesNanoplatforms for cancer theranosticsAdvancements in Transdermal Drug Delivery