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QbD based approach for formulation development of spray dried microparticles of erlotinib hydrochloride for sustained release

Govind Soni, Khushwant S. Yadav, Mahesh Gupta

2020Journal of Drug Delivery Science and Technology34 citationsDOI

Topics & Concepts

Critical quality attributesQuality by DesignBox–Behnken designErlotinibMaterials scienceParticle sizeSpray dryingPolyvinyl alcoholChromatographyProcess engineeringResponse surface methodologyChemistryChemical engineeringMedicineComposite materialEngineeringCancerEpidermal growth factor receptorInternal medicineDrug Solubulity and Delivery SystemsProtein purification and stabilityInhalation and Respiratory Drug Delivery
QbD based approach for formulation development of spray dried microparticles of erlotinib hydrochloride for sustained release | Litcius