Arabinose- and xylose-modified analogs of 2′,3′-cGAMP act as STING agonists
Wei Xie, Lodoe Lama, Xuejing Yang, Vitaly Kuryavyi, Shibani Bhattacharya, Ilona Nudelman, Guangli Yang, Ouathek Ouerfelli, J. Fraser Glickman, Roger A. Jones, Thomas Tuschl, Dinshaw J. Patel
Topics & Concepts
StingStimulator of interferon genesNucleaseArabinoseXyloseChemistryBiochemistryBiologyPharmacologyGeneInnate immune systemReceptorAerospace engineeringEngineeringFermentationinterferon and immune responsesImmune Response and InflammationViral Infections and Vectors