Rongalite as a Sulfone Source: Sulfonylation of <i>para</i>‐Quinone Methides and Alkyl/allyl Halides
Someshwar B. Kale, Popat K. Jori, Utpal Das
Abstract
A one-pot three-component reaction using p-quinone methides, rongalite and alkyl/allyl halides has been described. The corresponding unsymmetrical sulfones were obtained in good yields under mild reaction conditions in the absence of any metal, base or any other additive.
Topics & Concepts
SulfoneAlkylHalideChemistryQuinoneMedicinal chemistryOrganic chemistrySulfur-Based Synthesis TechniquesSynthesis of Indole DerivativesChemical Synthesis and Reactions